Elabscience

PRMT6 Polyclonal Antibody

Product Code:
 
E-AB-63865
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Immunofluorescence (IF)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunofluorescence analysis of U2OS cells using PRMT6 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Immunofluorescence analysis of U2OS cells using PRMT6 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

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CodeSizePrice
E-AB-63865-60uL60uL£224.00
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E-AB-63865-120uL120uL£317.00
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E-AB-63865-200uL200uL£465.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
PRMT6
Background:
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human PRMT6 (NP_060607.2).
Purification method:
Affinity purification
Target Synonym:
PRMT6;HRMT1L6
UNIProt ID:
Q96LA8

Documents