Elabscience

ACTN1 Polyclonal Antibody

Product Code:
 
E-AB-70225
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western Blot analysis of various samples using ACTN1 Polyclonal Antibody at dilution of 1:2000.
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Western Blot analysis of various samples using ACTN1 Polyclonal Antibody at dilution of 1:2000.

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E-AB-70225-60uL60uL£184.00
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E-AB-70225-120uL120uL£251.00
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E-AB-70225-200uL200uL£351.00
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This product comes from: China.
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Further Information

Abbreviation:
ACTN1
Background:
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
102-107kDa
Concentration:
0.66 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:3000
Immunogen:
Recombinant protein corresponding to Mouseα-actinin1
ObservedMW:
110kDa
Purification method:
Affinity purification
Target Synonym:
actinin 1 smooth muscle;Actinin alpha 1;actinin;alpha 1;ACTN 1;Actn1;ACTN1;Alpha Actinin 1;Alpha actinin cytoskeletal isoform;Alpha-actinin cytoskeletal isoform;Alpha-actinin-1;BDPLT15;F actin cross linking protein;F-actin cross-linking protein;FLJ40884;FLJ54432;Non muscle alpha actinin 1;Non-muscle alpha-actinin-1
UNIProt ID:
P12814,Q7TPR4,Q9Z1P2

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