Elabscience

ACTL6A Polyclonal Antibody

Product Code:
 
E-AB-60939
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using ACTL6A Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of various cell lines using ACTL6A Polyclonal Antibody at dilution of 1:1000.

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E-AB-60939-60uL60uL£210.00
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E-AB-60939-120uL120uL£291.00
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E-AB-60939-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
ACTL6A
Background:
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
43kDa/47kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human ACTL6A (NP_004292.1).
ObservedMW:
48kDa
Purification method:
Affinity purification
Target Synonym:
ACTL6A;ACTL6;ARPN-BETA;Arp4;BAF53A;INO80K
UNIProt ID:
O96019

Documents