Elabscience

TTR Monoclonal Antibody

Product Code:
 
E-AB-22254
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Mouse
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
Clone:2B12
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western Blot analysis of Human serum using TTR Monoclonal Antibody at dilution of 1:2000.
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Immunohistochemistry of paraffin-embedded Human Thyroid tissue using TTR Monoclonal Antibody at dilution of 1:200.
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Western Blot analysis of Human serum using TTR Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human Thyroid tissue using TTR Monoclonal Antibody at dilution of 1:200.

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E-AB-22254-20uL20uL£125.00
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E-AB-22254-60uL60uL£172.00
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E-AB-22254-120uL120uL£237.00
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E-AB-22254-200uL200uL£344.00
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Further Information

Abbreviation:
TTR Mouse (2B12)
Background:
This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-2000, IHC 1:50-300
Immunogen:
Recombinant Protein of TTR
ObservedMW:
16kDa
Purification method:
Protein A purification
Target Synonym:
Amyloid polyneuropathy;Amyloidosis I;ATTR;Carpal tunnel syndrome 1;CTS;CTS1;Dysprealbuminemic euthyroidal hyperthyroxinemia;Dystransthyretinemic hyperthyroxinemia;Epididymis luminal protein 111;HEL111;HsT2651;PALB;Prealbumin amyloidosis type I;Prealbumin;Prealbumin Thyroxine-binding;Senile systemic amyloidosis;TBPA;Thyroxine binding prealbumin;Transthyretin;TTHY;TTR;TTR protein
UNIProt ID:
P02766

Documents