Elabscience

MFN2 Polyclonal Antibody

Product Code:
 
E-AB-32025
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Western Blot analysis of HuvEc cells using Mfn2 Polyclonal Antibody at dilution of 1:1000.
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Western Blot analysis of HuvEc cells using Mfn2 Polyclonal Antibody at dilution of 1:1000.

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E-AB-32025-20uL20uL£125.00
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E-AB-32025-60uL60uL£172.00
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E-AB-32025-120uL120uL£237.00
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E-AB-32025-200uL200uL£344.00
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  • Further Information
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Further Information

Abbreviation:
Mfn2
Background:
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
86kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Immunogen:
Synthesized peptide derived from the Internal region of human Mfn2.
ObservedMW:
86kDa
Purification method:
Affinity purification
Target Synonym:
CMT2A;CMT2A2;CPRP 1;CPRP1;EC 3.6.5.-;Fzo;HSG;hyperplasia suppressor gene;Hypertension related protein 1;KIAA0214;MARF;MFN 2;Mfn2;MFN2;Mitochondrial assembly regulatory factor;Mitofusin-2;Mitofusin2;Transmembrane GTPase MFN2
UNIProt ID:
O95140

Documents

References

  • https://cancerci.biomedcentral.com/articles/10.1186/s12935-021-02137-x