Elabscience

ERN2 Polyclonal Antibody

Product Code:
 
E-AB-16413
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
-20°C
1 / 2
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ERN2 Polyclonal Antibody at dilution 1:40
2 / 2
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ERN2 Polyclonal Antibody at dilution 1:40
❮❯

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ERN2 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ERN2 Polyclonal Antibody at dilution 1:40

No additional charges, what you see is what you pay! *

CodeSizePrice
E-AB-16413-20uL20uL£125.00
Quantity:
E-AB-16413-60uL60uL£172.00
Quantity:
E-AB-16413-120uL120uL£237.00
Quantity:
E-AB-16413-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
ERN2
Background:
The accumulation of unfolded proteins within the endoplasmic recticulum (ER) of yeast and mammalian cells activates the unfolded protein response (UPR) pathway and leads to the transcription of ER-specific genes involved in protein folding. The activation of the UPR requires the ER transmembrane kinase IRE1p (for inositol-requiring and ER-to-nucleus signaling protein). IRE1α and IRE1β are two mammalian homologs of the yeast IRE1p. These related proteins localize to the ER lumen and contain both a short transmembrane domain that spans the ER membrane and a cytosolic Ser/Thr kinase domain. IRE1 activation involves the oligomerization and trans-phosphorylation of the cytosolic portion of the proteins, which then potentiates its intrinsic kinase activity and, in turn, stimulates transcription of UPR-targeted genes.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1.1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human ERN2
Purification method:
Affinity purification
Target Synonym:
IRE1b;IRE1-BETA
UNIProt ID:
Q76MJ5

Documents