Elabscience

BCL-x Polyclonal Antibody

Product Code:
 
E-AB-30640
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Western Blot analysis of 293T cells using Bcl-x Polyclonal Antibody at dilution of 1:500.
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Western Blot analysis of 293T cells using Bcl-x Polyclonal Antibody at dilution of 1:500.

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E-AB-30640-20uL20uL£125.00
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E-AB-30640-60uL60uL£172.00
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E-AB-30640-120uL120uL£237.00
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E-AB-30640-200uL200uL£344.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
Bcl-x
Background:
Bcl x is a member of the Bcl 2 family of proteins, which function as regulators of apoptosis. It may provide neuroprotection against ischemic brian injury. Bcl x has two isoforms, Bcl xl (long) a 241 amino acid protein and Bcl xs (short) a 178 amino acid protein lacking a 63 amino acid domain that is well conserved among members of the Bcl2 family. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
26kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Immunogen:
Synthesized peptide derived from human Bcl-x around the non-phosphorylation site of Thr47.
ObservedMW:
30kDa
Purification method:
Affinity purification
Target Synonym:
Apoptosis regulator Bcl X;Apoptosis regulator Bcl-X;Apoptosis regulator BclX;B cell lymphoma 2 like;B2CL1;Bcl 2 like 1 protein;Bcl X;Bcl xL;BCL XL/S;Bcl xS;Bcl-2-like protein 1;Bcl2 Like 1;Bcl2 related gene;Bcl2-L-1;BCL2L;Bcl2l1;BCLX;BclXL;BclXs;DKFZp781P2092;PPP1R52;Protein phosphatase 1 regulatory subunit 52
UNIProt ID:
Q07817

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