Elabscience

ASAH1 Polyclonal Antibody

Product Code:
 
E-AB-10959
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
1 / 3
Western Blot analysis of Human lung cancer tissue, Human fetal brain and fetal lung tissue using ASAH1 Polyclonal Antibody at dilution of 1:850
2 / 3
Immunohistochemistry of paraffin-embedded Human cervical cancer using ASAH1 Polyclonal Antibody at dilution of 1:50
3 / 3
Immunohistochemistry of paraffin-embedded Human breast cancer using ASAH1 Polyclonal Antibody at dilution of 1:50
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Western Blot analysis of Human lung cancer tissue, Human fetal brain and fetal lung tissue using ASAH1 Polyclonal Antibody at dilution of 1:850
Immunohistochemistry of paraffin-embedded Human cervical cancer using ASAH1 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human breast cancer using ASAH1 Polyclonal Antibody at dilution of 1:50

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E-AB-10959-20uL20uL£125.00
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E-AB-10959-60uL60uL£172.00
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E-AB-10959-120uL120uL£237.00
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E-AB-10959-200uL200uL£344.00
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  • Further Information
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Further Information

Abbreviation:
ASAH1
Background:
This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
45kDa
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human ASAH1
Purification method:
Affinity purification
Target Synonym:
AC;ACDase;Acid CDase;Acid ceramidase;Acid ceramidase precursor;Acid ceramidase subunit beta;Acylsphingosine deacylase;ASAH 1;ASAH;ASAH1;ASAH1;FLJ21558;FLJ22079;N acylsphingosine amidohydrolase (acid ceramidase) 1;N acylsphingosine amidohydrolase 1;N acylsphingosine amidohydrolase;N-acylsphingosine amidohydrolase;N-acylsphingosine deacylase;PHP;PHP32;Putative 32 kDa heart protein;SMAPME
UNIProt ID:
Q13510

Documents

References

  • https://www.mdpi.com/2073-4409/11/16/2524
  • https://pubmed.ncbi.nlm.nih.gov/34473432/
  • https://pubmed.ncbi.nlm.nih.gov/33914445/