Elabscience

ERCC6 Polyclonal Antibody

Product Code:
 
E-AB-91996
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using ERCC6 Polyclonal Antibody at 1:1000 dilution.
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Immunohistochemistry of paraffin-embedded human tonsil using ERCC6 Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
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Western blot analysis of extracts of various cell lines using ERCC6 Polyclonal Antibody at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded human tonsil using ERCC6 Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

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E-AB-91996-60uL60uL£210.00
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E-AB-91996-120uL120uL£291.00
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E-AB-91996-200uL200uL£431.00
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Further Information

Abbreviation:
ERCC6
Background:
This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
168kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
A synthetic peptide of human ERCC6
ObservedMW:
168KDa
Purification method:
Affinity purification
Target Synonym:
CSB;CKN2;COFS;ARMD5;COFS1;POF11;RAD26;UVSS1;CSB-PGBD3;ERCC6
UNIProt ID:
Q03468

Documents