Elabscience

RRP8 Polyclonal Antibody

Product Code:
 
E-AB-92293
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using RRP8 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using RRP8 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-92293-60uL60uL£210.00
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E-AB-92293-120uL120uL£291.00
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E-AB-92293-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
RRP8
Background:
Essential component of the eNoSC (energy-dependent nucleolar silencing complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+/NADP(+ ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2 by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
50kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human RRP8
ObservedMW:
58KDa
Purification method:
Affinity purification
Target Synonym:
NML; KIAA0409
UNIProt ID:
O43159

Documents