NSJ Bioreagents

IL-1B Antibody

Product Code:
 
NSJ-F53698
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
614CT4.3.1
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the IL-1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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IL-1B antibody 293 cell lysate transiently transfected with the IL1B gene. Predicted molecular weight: 31 kDa (precursor) and 17 kDa (mature).

IL-1B antibody 293 cell lysate transiently transfected with the IL1B gene. Predicted molecular weight: 31 kDa (precursor) and 17 kDa (mature).

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CodeSizePrice
NSJ-F53698-0.1ML0.1 ml£502.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
Western blot: 1:2000-1:4000
Application Note:
Titration of the IL-1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq].
Format:
Ascites
Formulation:
In ascites with 0.09% sodium azide
Immunogen:
A portion of amino acids 148-174 from the human protein was used as the immunogen for this IL-1B antibody.
Limitation:
This IL-1B antibody is available for research use only.
Purity:
Ascites
Uniprot #:
P01584

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