NSJ Bioreagents

S100B Antibody

Product Code:
 
NSJ-F54011
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse lgG2b
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
5G3-C11
Regulatory Status:
 
RUO
Target Species:
 
Rat
Application:
 
Western Blot (WB)
Storage:
 
Store the S100 beta antibody at -20oC.
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Western blot testing of rat brain lysate with S100 beta antibody at 1:500 diluted. Predicted molecular weight ~11 kDa.
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Western blot testing of rat brain lysate with S100 beta antibody at 1:500 diluted. Predicted molecular weight ~11 kDa.

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CodeSizePrice
NSJ-F54011-0.1ML0.1 ml£502.00
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Further Information

Application Details:
Western blot: 1:500
Application Note:
The stated application concentrations are suggested starting points. Titration of the S100 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Format:
Purified
Formulation:
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Immunogen:
A S100B synthetic peptide was used as the immunogen for this S100 beta antibody.
Limitation:
This S100 beta antibody is available for research use only.
Purity:
Protein G affinity
Uniprot #:
P04271

Documents