Mouse Anti-Human CD130 Monoclonal Antibody, Clone B-K11, Azide free

Product Code:

852.100.000

Product Group:

Primary Antibodies

Supplier:

Diaclone

Host Type:

Mouse

Antibody Isotype:

IgG2b

Antibody Clonality:

Monoclonal

Antibody Clone:

B-K11

Regulatory Status:

RUO

Target Species:

Human

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Code	Size	Price

852.100.000

200ug/200ul

£232.00

Quantity:

Prices exclude any Taxes / VAT

Further Information

Antigen:

CD130 / gp130

Antigen Synonyms:

gp130

Conjugate:

Azide free

Format:

Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free

Hybridoma:

Myeloma X63/AG.8653 x Balb/c spleen cells

Immunisation:

Natural soluble gp130

Reactivity:

Human

Research Area:

Cytokine / Chemokine ReceptorsCD Markers

Specificity:

Recognises the Gp130 common subunit for IL-6 IL-11 OSM LIF CNTF CT-1 receptors a 130-140 kDa protein

Workshop:

Chevalier S. et al. J Biol Chem.1996; 271(25): 14764-72.. Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein. https://www.ncbi.nlm.nih.gov/pubmed/8662918
Guillet C. et al. J Neurosci.1999; 19(4): 1257-62.. Ciliary neurotrophic factor is a regulator of muscular strength in aging. https://www.ncbi.nlm.nih.gov/pubmed/9952403
M?ller-Newen G. et al. J. Biol. Chem. 2000; 275 (7) : 4578 - 4586. Studies on the interleukin-6-type cytokine signal transducer gp130 reveal a novel mechanism of receptor activation by monoclonal antibodies. https://www.ncbi.nlm.nih.gov/pubmed/10671483
Muller-Newen G. et al. Eur J Biochem1996; 236(3): 837-42.. Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing. https://www.ncbi.nlm.nih.gov/pubmed/8665902