Mouse Anti-Human IL-6 Monoclonal Antibody, Clone B-F6, Azide free

Product Code:

855.060.005

Product Group:

Primary Antibodies

Supplier:

Diaclone

Host Type:

Mouse

Antibody Isotype:

IgG1

Antibody Clonality:

Monoclonal

Antibody Clone:

B-F6

Regulatory Status:

RUO

Target Species:

Human

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Code	Size	Price

855.060.005

500ug/500ul

£419.00

Quantity:

Prices exclude any Taxes / VAT

Further Information

Antigen:

IL-6

Conjugate:

Azide free

Format:

Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free

Hybridoma:

Myeloma X63/AG.8653 x Balb/c spleen cells

Immunisation:

Recombinant human IL-6

Reactivity:

Human Mouse

Research Area:

Cytokines / Growth Factors

Specificity:

Recognises both natural and recombinant human IL-6

Kube D. et al. Blood2001; 98(3): 762-70.. STAT3 is constitutively activated in Hodgkin cell lines. https://www.ncbi.nlm.nih.gov/pubmed/11468177
Voorzanger N. et al. Cancer Res.1996; 56(23): 5499-505.. Interleukin (IL)-10 and IL-6 are produced in vivo by non-Hodgkin's lymphoma cells and act as cooperative growth factors. https://www.ncbi.nlm.nih.gov/pubmed/8968107
Wijdenes J. et al. Eur. J. Immunol.1995; 25 : 3474-3481. Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies. https://www.ncbi.nlm.nih.gov/pubmed/8566040
Wijdenes J. et al. Mol Immuno.1991;l 28(11): 1183-92.. Human recombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies. https://www.ncbi.nlm.nih.gov/pubmed/1720501
Zunino S. J. et al. Am J Pathol.1996; 149(2): 653-63.. Immunodetection of histone epitopes correlates with early stages of apoptosis in activated human peripheral T lymphocytes. https://www.ncbi.nlm.nih.gov/pubmed/8702003