NSJ Bioreagents

Pan-HLA Antibody MHC II (DP/DQ/DR)

Product Code:
 
NSJ-V5135SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
rHLA-Pan/8847
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Aliquot the Pan-HLA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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IHC staining of FFPE human ovarian cancer tissue with Pan-HLA antibody (clone rHLA-Pan/8847). Inset: PBS instead of primary, secondary negative control.~
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SDS-PAGE analysis of purified, BSA-free Pan-HLA antibody (clone rHLA-Pan/8847) as con

IHC staining of FFPE human ovarian cancer tissue with Pan-HLA antibody (clone rHLA-Pan/8847). Inset: PBS instead of primary, secondary negative control.~
SDS-PAGE analysis of purified, BSA-free Pan-HLA antibody (clone rHLA-Pan/8847) as con

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NSJ-V5135SAF-100UG100 ug£534.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Description:
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36kDa) and a beta chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Priess cells (a human B cell line) were used as the immunogen for the Pan-HLA antibody.
Limitation:
This Pan-HLA antibody is available for research use only.
Localization:
Cell Surface
Purity:
Protein A/G affinity
Uniprot #:
P04440, P01908, P01909, P01920, P01903

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