ProSci

SARS-COV-2 Spike S1 Protein Antibody [7G2R4]

Product Code:
 
PSI-11-104
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
7G2R4
Regulatory Status:
 
RUO
Target Species:
 
Virus
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
Blue Ice
Storage:
 
This antibody can be stored at 2°C to -8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
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This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
❮❯

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

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PSI-11-104-0.1mg0.1 mg£765.00
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Further Information

Application Note:
SARS-CoV-2 Spike S1 Sanwich ELISA Immunoassay:

ELISA Capture: Recommended Concentration: 1-4ug/mL, Sample: SARS-COV-2 Spike S1 Protein Antibody(CAP)

ELISA Detection: Recommended Concentration: 0.05-0.2ug/mL, Sample: SARS-COV-2 Spike S1 Protein Antibody(DET)

Standard: Recommended Concentration: 156-10000pg/mL, Sample: Recombinant SARS-COV-2 Spike S1 Protein with His tag

Background:
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It's been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate
Buffer:
Supplied as a 0.2um filtered solution in PBS, pH 7.4.
Concentration:
1mg/ml
Conjugate:
Unconjugated
Immunogen:
HEK293 derived SARS-COV-2 SPIKE S1, amino acids Val16-Arg685
NCBI Gene ID #:
43740568
NCBI Official Name:
surface glycoprotein
NCBI Official Symbol:
S
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Liquid
Protein Accession #:
YP_009724390.1
Protein GI Number:
1796318598
Purification:
Affinity Purified, Endotoxin Level: < 1.0 EU/ug of the protein by LAL method.
Swissprot #:
P0DTC2
User Note:
Optimal dilutions for each application to be determined by the researcher.