MBL

MCM7 Rabbit mAb

Product Code:
 
MBL-CNA11325S
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
ARC0573
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
 
ice pack : 2 to 4°C temperature range.
Storage:
 
Store at -20°C
 

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MBL-CNA11325S100 uL£442.00
Quantity:
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This product comes from: United States.
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Further Information

Application Note:
WB,1:500 - 1:1000 | IF/ICC,1:50 - 1:200 | IP,1:500 - 1:1000
Background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this Protein A Affinity purificationnd MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Conjugate:
Unconjugated
Formulation:
PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol
Gene Accession Number:
MCM7
Gene ID:
4176
GeneID: Human:
4176
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human MCM7 (P33993).
Molecular Weight:
81kDa
Peptide Sequence:
YTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDE

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