MBL

FGD1 Rabbit pAb

Product Code:
 
MBL-CNA16374T
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
ice pack : 2 to 4°C temperature range.
Storage:
 
Store at -20°C
 

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CodeSizePrice
MBL-CNA16374T100 uL£442.00
Quantity:
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This product comes from: United States.
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Further Information

Application Note:
WB,1:500 - 1:2000 | IHC-P,1:50 - 1:100 | IF/ICC,1:50 - 1:100
Background:
This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of the faciogenital dysplasia in Aarskog-Scott syndrome and a syndromatic form of X-linked cognitive disability.
Conjugate:
Unconjugated
Formulation:
PBS with 0.01% thimerosal, 50% glycerol
Gene Accession Number:
FGD1
Gene ID:
2245
GeneID: Human:
2245
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FGD1 (NP_004454.2).
Molecular Weight:
107kDa
Peptide Sequence:
LLNSTNREDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLVYDNNRSNRVCTDCYVALHGVPGSSPACS

Documents