CDKN1B/p27KIP1 Rabbit pAb

Product Code:

MBL-CNA16633T

Product Group:

Primary Antibodies

Supplier:

MBL

Host Type:

Rabbit

Antibody Isotype:

IgG

Antibody Clonality:

Polyclonal

Regulatory Status:

RUO

Target Species:

Human
Mouse
Rat

Applications:

Immunohistochemistry- Paraffin Embedded (IHC-P)
Western Blot (WB)

Shipping:

ice pack : 2 to 4°C temperature range.

Storage:

Store at -20°C

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Code	Size	Price

MBL-CNA16633T

100 uL

£442.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Application Note:

WB,1:500 - 1:1000 | IHC-P,1:50 - 1:200

Background:

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).

Conjugate:

Unconjugated

Formulation:

PBS with 0.01% thimerosal, 50% glycerol

Gene Accession Number:

CDKN1B

Gene ID:

1027

GeneID: Human:

1027

Immunogen:

A synthetic peptide corresponding to a sequence within amino acids 100-198 of human CDKN1B/p27KIP1 (NP_004055.1).

Molecular Weight:

22kDa

Peptide Sequence:

KVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT

Documents

Datasheet