MBL

PHOX2B Rabbit mAb

Product Code:
 
MBL-CNA6816S
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
ARC1420
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
ice pack : 2 to 4°C temperature range.
Storage:
 
Store at -20°C
 

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MBL-CNA6816S100 uL£442.00
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This product comes from: United States.
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Further Information

Application Note:
WB,1:500 - 1:1000
Background:
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.
Conjugate:
Unconjugated
Formulation:
PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 215-314 of human PHOX2B (NP_003915.2).
Molecular Weight:
32kDa
Peptide Sequence:
GGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQGWAPGPGPITSIPDSLGGPFASVLSSLQRPNGAKAALVKSSMF

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