MBL

Phospho-Chk1-S345 Rabbit pAb

Product Code:
 
MBL-CNAP0578T
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
ice pack : 2 to 4°C temperature range.
Storage:
 
Store at -20°C
 

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CodeSizePrice
MBL-CNAP0578T100 uL£442.00
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This product comes from: United States.
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Further Information

Application Note:
WB,1:100 - 1:500
Background:
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Conjugate:
Unconjugated
Formulation:
PBS with 0.01% thimerosal, 50% glycerol
Immunogen:
A synthetic phosphorylated peptide around S345 of human Chk1 (NP_001265.2).
Molecular Weight:
54kDa
Peptide Sequence:
SFSQP

Documents