MBL

Phospho-AKT1-T450 Rabbit mAb

Product Code:
 
MBL-CNAP0980S
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
ARC1524
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
ice pack : 2 to 4°C temperature range.
Storage:
 
Store at -20°C
 

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MBL-CNAP0980S100 uL£442.00
Quantity:
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This product comes from: United States.
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Further Information

Application Note:
WB,1:500 - 1:2000
Background:
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded Protein A Affinity purificationlso anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.
Conjugate:
Unconjugated
Formulation:
PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol
Immunogen:
A synthetic phosphorylated peptide around T450 of human Akt1 (P31749).
Molecular Weight:
56kDa
Peptide Sequence:
TITPP

Documents