MBL

Phospho-HSP27/HSPB1-S82 Rabbit mAb

Product Code:
 
MBL-CNAP1031S
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Antibody Clone:
 
ARC1576
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
ice pack : 2 to 4°C temperature range.
Storage:
 
Store at -20°C
 

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CodeSizePrice
MBL-CNAP1031S100 uL£442.00
Quantity:
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Further Information

Application Note:
WB,1:500 - 1:2000
Background:
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This Protein A Affinity purificationnd the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
Conjugate:
Unconjugated
Formulation:
PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol
Immunogen:
A synthetic phosphorylated peptide around S82 of human HSP27/HSPB1HSPB1 (P04792).
Molecular Weight:
23kDa
Peptide Sequence:
QLSSG

Documents