NSJ Bioreagents

mGluR5 Antibody / Glutamate Metabotropic Receptor 5 / GRM5

Product Code:
 
NSJ-RQ7664
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
After reconstitution, the mGluR5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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Western blot testing of 1) human U-87 MG, 2) human 293T and 3) rat C6 cell lysate with mGluR5 antibody. Predicted molecular weight ~132 kDa but may be observed at higher molecular weights due to glycosylation.
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Western blot testing of 1) human U-87 MG, 2) human 293T and 3) rat C6 cell lysate with mGluR5 antibody. Predicted molecular weight ~132 kDa but may be observed at higher molecular weights due to glycosylation.

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NSJ-RQ7664-100ug100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details:
Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Metabotropic glutamate receptor 5 is a G protein-coupled receptor that in humans is encoded by the GRM5 gene. It is mapped to 11q14.2-q14.3. This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids K443-S1050) was used as the immunogen for the mGluR5 antibody.
Purity:
Antigen affinity purified
Uniprot #:
P41594