NSJ Bioreagents

SPOP Antibody / Speckle-type POZ protein

Product Code:
 
NSJ-RQ7666
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the SPOP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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Western blot testing of human 1) PC-3, 2) HeLa, 3) HepG2, 4) MOLT4 and 5) K562 cell lysate with SPOP antibody. Predicted molecular weight ~42 kDa.

Western blot testing of human 1) PC-3, 2) HeLa, 3) HepG2, 4) MOLT4 and 5) K562 cell lysate with SPOP antibody. Predicted molecular weight ~42 kDa.

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NSJ-RQ7666-100ug100 ug£535.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
Western blot: 0.5-1ug/ml
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Speckle-type POZ protein is a protein that in humans is encoded by the SPOP gene. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids LHSADQLKTQAVDFINYHASDVLE from the human protein were used as the immunogen for the SPOP antibody.
Localisation:
Nuclear
Purity:
Antigen affinity purified
Uniprot #:
O43791