NSJ Bioreagents

Fibroblast growth factor receptor 2 Antibody / FGFR2

Product Code:
 
NSJ-RQ7691
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
 
After reconstitution, the Fibroblast growth factor receptor 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
1 / 2
Flow cytometry testing of human U-2 OS cells with Fibroblast growth factor receptor 2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Fibroblast growth factor receptor 2 antibody.
2 / 2
Western blot testing of human 1) MCF7, 2) HeLa and 3) K562 cell lysate with Fibroblast growth factor receptor 2 antibody. Predicted molecular weight: 80-120 kDa. The observed size may be larger due to glycosylation.
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Flow cytometry testing of human U-2 OS cells with Fibroblast growth factor receptor 2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Fibroblast growth factor receptor 2 antibody.
Western blot testing of human 1) MCF7, 2) HeLa and 3) K562 cell lysate with Fibroblast growth factor receptor 2 antibody. Predicted molecular weight: 80-120 kDa. The observed size may be larger due to glycosylation.

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NSJ-RQ7691-100ug100 ug£535.00
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Further Information

Application Details:
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor(FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian(amniote) embryogenesis is discussed.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids R22-T821) was used as the immunogen for the Fibroblast growth factor receptor 2 antibody.
Purity:
Antigen affinity purified
Uniprot #:
P21802