NSJ Bioreagents

CRMP2 Antibody / DPYSL2

Product Code:
 
NSJ-RQ7974
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
 
After reconstitution, the CRMP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
1 / 2
Immunofluorescent staining of FFPE human A549 cells with CRMP2 antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
2 / 2
Western blot testing of 1) human U-87 MG, 2) human SH-SY5Y, 3) rat brain and 4) mouse brain tissue lysate with CRMP2 antibody. Predicted molecular weight ~62 kDa.
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Immunofluorescent staining of FFPE human A549 cells with CRMP2 antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
Western blot testing of 1) human U-87 MG, 2) human SH-SY5Y, 3) rat brain and 4) mouse brain tissue lysate with CRMP2 antibody. Predicted molecular weight ~62 kDa.

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CodeSizePrice
NSJ-RQ7974-100ug100 ug£535.00
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Further Information

Application Details:
Western blot: 0.5-1ug/ml,Immunofluorescence: 5ug/ml
Description:
Dihydropyrimidinase-related protein 2, also called Collapsin response mediator protein 2 (CRMP2), is an enzyme that in humans is encoded by the DPYSL2 gene. This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amio acids KDRFQLTDCQIYEVLSV were used as the immunogen for the CRMP2 antibody.
Localisation:
Cytoplasmic, cell membrane
Purity:
Antigen affinity purified
Uniprot #:
Q16555