NSJ Bioreagents

APLP1 Antibody

Product Code:
 
NSJ-RQ8086
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
 
After reconstitution, the APLP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
1 / 2
Flow cytometry testing of fixed and permeabilized human SiHa cells with APLP1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= APLP1 antibody.
2 / 2
Western blot testing of 1) human SH-SY5Y, 2) human U-87 MG, 3) rat brain, 4) rat liver, 5) rat RH35, 6) mouse brain and 7) mouse Neuro-2a cell lysate with APLP1 antibody. Predicted molecular weight ~72 kDa but may be observed at higher molecular weights due to glycosylation.
❮❯

Flow cytometry testing of fixed and permeabilized human SiHa cells with APLP1 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= APLP1 antibody.
Western blot testing of 1) human SH-SY5Y, 2) human U-87 MG, 3) rat brain, 4) rat liver, 5) rat RH35, 6) mouse brain and 7) mouse Neuro-2a cell lysate with APLP1 antibody. Predicted molecular weight ~72 kDa but may be observed at higher molecular weights due to glycosylation.

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CodeSizePrice
NSJ-RQ8086-100ug100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details:
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Description:
Amyloid-precursor-like protein 1 (APLP1) is a membrane-associated glycoprotein, whose gene is homologous to the APP gene, which has been shown to be involved in the pathogenesis of Alzheimer's disease. APLP1 is predominantly expressed in brain, particularly in the cerebral cortex postsynaptic absorbance. The human gene has been mapped to chromosomal region 19q13.1. The gene is 11.8 kb long and contains 17 exons. APLP1 has been considered a candidate gene for CNF. All exon regions of the gene were amplified by the polymerase chain reaction and sequenced from DNA of CNF patients. No differences were observed between CNF patients and controls, suggesting that mutations in APLP1 are not involved in the etiology of CNF.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids Q55-Q566) was used as the immunogen for the APLP1 antibody.
Purity:
Antigen affinity purified
Uniprot #:
P51693