NSJ Bioreagents

Mu-type Opioid Receptor Antibody / OPRM1

Product Code:
 
NSJ-RQ8105
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
After reconstitution, the MOR-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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Western blot testing of 1) human SH-SY5Y, 2) human K562, 3) human Jurkat, 4) human U-251, 5) rat brain, 6) rat heart, 7) mouse brain and 8) mouse heart tissue lysate with MOR-1 antibody. Predicted molecular weight: 35-55 kDa (multiple isoforms) but may be observed at higher molecular weights due to glycosylation.
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Western blot testing of 1) human SH-SY5Y, 2) human K562, 3) human Jurkat, 4) human U-251, 5) rat brain, 6) rat heart, 7) mouse brain and 8) mouse heart tissue lysate with MOR-1 antibody. Predicted molecular weight: 35-55 kDa (multiple isoforms) but may be observed at higher molecular weights due to glycosylation.

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NSJ-RQ8105-100ug100 ug£535.00
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Further Information

Application Details:
Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml
Description:
This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids N33-H321) was used as the immunogen for the MOR-1 antibody.
Purity:
Antigen affinity purified
Uniprot #:
P35372