NSJ Bioreagents

NECAB3 Antibody / N-terminal EF-hand calcium-binding protein 3

Product Code:
 
NSJ-RQ8230
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
 
After reconstitution, the NECAB3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
1 / 2
Flow cytometry testing of fixed and permeabilized human U-251 cells with NECAB3 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= NECAB3 antibody.
2 / 2
Western blot testing of 1) human HeLa, 2) human 293T, 3) rat brain and 4) mouse brain tissue lysate with NECAB3 antibody. Predicted molecular weight ~44 kDa.
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Flow cytometry testing of fixed and permeabilized human U-251 cells with NECAB3 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= NECAB3 antibody.
Western blot testing of 1) human HeLa, 2) human 293T, 3) rat brain and 4) mouse brain tissue lysate with NECAB3 antibody. Predicted molecular weight ~44 kDa.

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CodeSizePrice
NSJ-RQ8230-100ug100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details:
Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml
Description:
N-terminal EF-hand calcium-binding protein 3 is a protein that in humans is encoded by the NECAB3 gene. The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Format:
Antigen affinity purified
Formulation:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
E. coli-derived recombinant human protein (amino acids D97-D339) was used as the immunogen for the NECAB3 antibody.
Purity:
Antigen affinity purified
Uniprot #:
Q96P71