ProSci

GRTP1 Antibody

Product Code:
 
PSI-4591
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
1 / 1
Western blot analysis of GRTP1 in SK-N-SH cell lysate with GRTP1 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.
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Western blot analysis of GRTP1 in SK-N-SH cell lysate with GRTP1 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.

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CodeSizePrice
PSI-4591-0.02mg0.02mg£150.00
Quantity:
PSI-4591-0.1mg0.1mg£449.00
Quantity:
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Further Information

Additional Names:
GRTP1 Antibody: TBC1D6, TBC1D6, Growth hormone-regulated TBC protein 1, TBC1 domain family member 6
Application Note:
GRTP1 antibody can be used for detection of GRTP1 by Western blot at 1 μg/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
GRTP1 Antibody: Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment.
Background References:
  • Lu C, Kasik J, Stephan DA, et al. Grtp1, a novel gene regulated by growth hormone. Endocriniology2001; 142:4568-71.
  • Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science2008; 319:921-6.
Buffer:
GRTP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
GRTP1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human GRTP1.

The immunogen is located within amino acids 80 - 130 of GRTP1.
NCBI Gene ID #:
79774
NCBI Official Name:
growth hormone regulated TBC protein 1
NCBI Official Symbol:
GRTP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
EAX09206
Protein GI Number:
119629611
Purification:
GRTP1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
At least three isoforms of GRTP1 are known to exist; this antibody should recognize all isoforms.
Swissprot #:
Q5TC63
User NOte:
Optimal dilutions for each application to be determined by the researcher.