ProSci

ARHGAP39 Antibody

Product Code:
 
PSI-6445
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
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Western blot analysis of ARHGAP39 in A20 cell lysate with ARHGAP39 antibody at (A) 1 and (B) 2 μg/mL
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Western blot analysis of ARHGAP39 in A20 cell lysate with ARHGAP39 antibody at (A) 1 and (B) 2 μg/mL

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CodeSizePrice
PSI-6445-0.02mg0.02mg£150.00
Quantity:
PSI-6445-0.1mg0.1mg£449.00
Quantity:
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Further Information

Additional Names:
ARHGAP39 Antibody: CrGAP, Vilse, KIAA1688, Rho GTPase-activating protein 39
Application Note:
ARHGAP39 antibody can be used for detection of ARHGAP39 by Western blot at 1 - 2 μg/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Background:
ARHGAP39 Antibody: Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP39 (Rho GTPase activating protein 39) is a 1, 083 amino acid nuclear protein that contains one MyTH4 domain, one Rho GAP domain and two WW domains. It is encoded by a gene located on human chromosome 8, which is associated with a variety of diseases and malignancies. ARHGAP39 regulates robo signaling and plays important roles in axon guidance.
Background References:
  • Takai Y, Sasaki T, and Matozaki T. Small GTP-binding proteins. Physiol. Rev. 2001; 81:153-208.
  • Hu H, Li M, Labrador JP, et al. Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion. Proc. Natl. Acad. Sci. USA 2005; 102:4613-8
  • Nusbaum C, Mikkelsen TS, Zody MC, et al. DNA sequence and analysis of human chromosome 8. Nature 2006; 439:331-5
  • Lundström A, Gallio M, Englund C, et al. Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons. Genes Dev. 2004; 18:2161-71.
Buffer:
ARHGAP39 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ARHGAP39 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human ARHGAP39.

The immunogen is located within amino acids 880 - 930 of ARHGAP39.
NCBI Gene ID #:
80728
NCBI Official Name:
Rho GTPase activating protein 39
NCBI Official Symbol:
ARHGAP39
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_079527
Protein GI Number:
58331179
Purification:
ARHGAP39 Antibody is affinity chromatography purified via peptide column.
Research Area:
Neuroscience
SPECIFICITY:
ARHGAP39 antibody is predicted to not cross-react with other RhoGAP protein family members.
Swissprot #:
Q9C0H5
User NOte:
Optimal dilutions for each application to be determined by the researcher.