ProSci

RILPL1 Antibody

Product Code:
 
PSI-6495
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Western Blot (WB)
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Western blot analysis of RILPL1 in rat cerebellum tissue lysate with RILPL1 antibody at (A) 0.5 and (B) 1 μg/mL.
2 / 2
Immunofluorescence of RILPL1 in mouse brain cells with RILPL1 antibody at 20 μg/mL.
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Western blot analysis of RILPL1 in rat cerebellum tissue lysate with RILPL1 antibody at (A) 0.5 and (B) 1 μg/mL.
Immunofluorescence of RILPL1 in mouse brain cells with RILPL1 antibody at 20 μg/mL.

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CodeSizePrice
PSI-6495-0.02mg0.02mg£150.00
Quantity:
PSI-6495-0.1mg0.1mg£449.00
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Further Information

Additional Names:
RILPL1 Antibody: RLP1, GOSPEL, RLP1, RILP-like protein 1, Rab-interacting lysosomal-like protein 1
Application Note:
RILPL1 antibody can be used for detection of RILPL1 by Western blot at 0.5 and 1 μg/mL. Antibody can also be used for immunofluorescence starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
RILPL1 Antibody: While the function of the Rab interacting lysosomal protein-like 1 (RILPL1) remains unknown, the homologous protein RILP is a small GTPase that controls transport to endocytic compartments, suggesting RILPL1 may have similar functions. However, overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell, while overexpression of RILPL1 had no visible effect on the location or morphology of lysosomes.
Background References:
  • Cantalupo G, Alifano P, Roberti V, et al. Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes. EMBO J. 2001; 20:683-93
  • Wang T, Wong KK, and Hong W. A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. Mol. Biol. Cell 2004; 15:815-26
Buffer:
RILPL1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (94%)
Immunogen:
RILPL1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human RILPL1.

The immunogen is located within the last 50 amino acids of RILPL1.
NCBI Gene ID #:
353116
NCBI Official Name:
Rab interacting lysosomal protein-like 1
NCBI Official Symbol:
RILPL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
AAH89444
Protein GI Number:
195947382
Purification:
RILPL1 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
At least three isoforms of RILPL1 are known to exist; this antibody will detect the two shorter isoforms. RILPL1 antibody is predicted to not cross-react with RILP.
Swissprot #:
Q5EBL4
User NOte:
Optimal dilutions for each application to be determined by the researcher.