ProSci

MTERFD2 Antibody

Product Code:
 
PSI-7283
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
1 / 3
Western blot analysis of MTERFD2 in human small intestine tissue lysate with MTERFD2 antibody at 1 μg/mL.
2 / 3
Immunohistochemistry of MTERFD2 in human small intestine tissue with MTERFD2 antibody at 2.5 μg/ml.
3 / 3
Immunofluorescence of MTERFD2 in human small intestine tissue with MTERFD2 antibody at 20 μg/ml.
❮❯

Western blot analysis of MTERFD2 in human small intestine tissue lysate with MTERFD2 antibody at 1 μg/mL.
Immunohistochemistry of MTERFD2 in human small intestine tissue with MTERFD2 antibody at 2.5 μg/ml.
Immunofluorescence of MTERFD2 in human small intestine tissue with MTERFD2 antibody at 20 μg/ml.

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CodeSizePrice
PSI-7283-0.02mg0.02mg£150.00
Quantity:
PSI-7283-0.1mg0.1mg£449.00
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Further Information

Additional Names:
MTERFD2 Antibody: MTERF4, mTERF domain-containing protein 2, Mitochondrial transcription termination factor 4, MTERF4
Application Note:
MTERFD2 Antibody can be used for detection of MTERFD2 by Western blot at 1 μg/mL.

Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
MTERFD2 Antibody: Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD2 is targeted to the mitochondria and is ubiquitously expressed, with highest expression levels in fore- and midbrain, diencephalon, spinal cord, tongue, lung liver and kidney. MTERFD2 has been suggested to play a role in organ differentiation during embryogenesis. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.
Background References:
  • Fernandez-Silva P, et al. The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions. EMBO J. 1997; 16:1066-79.
  • Xu Q, Zhang F, He H, et al. Expression profile of mouse Mterfd2, a novel component of the mitochondrial transcription termination (MTERF) family. Genes Genet. Syst. 2011; 86:269-75.
  • Park CB, Asin-Cayuela J, Camara Y, et al. MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell 2007; 130:273-85.
Buffer:
MTERFD2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MTERFD2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MTERFD2 .

The immunogen is located within amino acids 260 - 310 of MTERFD2.
NCBI Gene ID #:
130916
NCBI Official Name:
MTERF domain containing 2
NCBI Official Symbol:
MTERFD2
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 42 kDa

Observed: 44 kDa
Protein Accession #:
NP_872307
Protein GI Number:
42740903
Purification:
MTERFD2 Antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell
SPECIFICITY:
At least three isoforms of MTERFD2 are known to exist. MTERFD2 antibody is predicted to not cross-react with other MTERFD protein family members.
Swissprot #:
Q7Z6M4
User NOte:
Optimal dilutions for each application to be determined by the researcher.