Further Information
GJC2, CX46.6, Cx47, GJA12, MGC105119, PMLDAR, HLD2, SPG44, LMPH1C
GJC2 antibody can be used for detection of GJC2 by ELISA at 1:312500. GJC2 antibody can be used for detection of GJC2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.
- Henneke, M., (2008) Neurology 70 (10), 748-754.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GJC2.
57165
gap junction protein, gamma 2, 47kDa
GJC2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
NP_065168
45439367
Antibody is purified by peptide affinity chromatography method.
Membrane ,Signal Transduction
Q5T442
Optimal dilutions for each application to be determined by the researcher.