ProSci

MUC1 Antibody

Product Code:
 
PSI-XW-8095
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Chicken
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
MUC1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Anti-MUC-1 IgY staining of Formalin-fixed and paraffin-embedded Esophogeal Cancer tissue. Affinity-purified IgY dilution: 1:100, Rabbit anti-IgY-Biotin dilution: 1:300. (Courtesy of Jessica Wang-Rodriguez MD, UCSD & VA San Diego Healthcare System.)<br><br>E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
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Anti-MUC-1 IgY staining of Formalin-fixed and paraffin-embedded Esophogeal Cancer tissue. Affinity-purified IgY dilution: 1:100, Rabbit anti-IgY-Biotin dilution: 1:300. (Courtesy of Jessica Wang-Rodriguez MD, UCSD & VA San Diego Healthcare System.)<br><br>E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

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PSI-XW-8095-0.05mg0.05mg£801.00
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Further Information

Additional Names:
PUM, Mucin-1, Breast carcinoma-associated antigen DF3, MUC-1, EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, ADMCKD, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC, Mucin1, Polymorphic epithelial mucin, Episialin, Tumor-associated mucin, Carcinoma-associated mucin, Tumor-associated epithelial membrane antigen, Peanut-reactive urinary mucin, CD227 ant
Application Note:
Mucin-1 antibody can be used for the detection of Mucin-1 by IHC and Western Blot, may also work for ELISA, ICC.
Background:
FUNCTION: isoform 5. The binding induces the phosphorylation of the isoform 7, alters cellular morphology and initiates cell signaling. Can bind to GRB2 adapter protein.

SUBUNIT: The cleaved form (only the isoform 1) of MUC1 forms a tight heterodimer with the released C-terminal peptide (which is first secreted to be extracellular).
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
199-244
NCBI Gene ID #:
4582
NCBI Official Name:
mucin 1, cell surface associated
NCBI Official Symbol:
MUC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
122.1 kDa (calculated)
Protein Accession #:
NP_002447.4
Protein GI Number:
65301117
Purification:
Immunoaffinity Purified
Swissprot #:
P15941
User NOte:
Optimal dilutions for each application to be determined by the researcher.