ProSci

Serotonin receptor 1B Antibody

Product Code:
 
PSI-46-355
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot and store at -20˚C. Minimize freezing and thawing.
1 / 1
46-355 (1ug/ml) staining of Human Cerebellum (A) and Mouse spinal cord (B) lysates (35ug protein in RIPA buffer). Detected by chemiluminescence.
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46-355 (1ug/ml) staining of Human Cerebellum (A) and Mouse spinal cord (B) lysates (35ug protein in RIPA buffer). Detected by chemiluminescence.

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PSI-46-355-0.1mg0.1mg£626.00
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Further Information

Additional Names:
HTR1B, 5-hydroxytryptamine (serotonin) receptor 1B, 5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 48kDa band observed in Human Brain (Cerebellum) and 48+45kDa band observed in Mouse Spinal Cord lysates (calculated MW of 43.6kDa according to NP_000854.1). Recommended concentration: 1-3ug/ml. Primary incubation was 1 hour.
Background References:
  • Svenningsson P, Chergui K, Rachleff I, Flajolet M, Zhang X, El Yacoubi M, Vaugeois JM, Nomikos GG, Greengard P. Alterations in 5-HT1B receptor function by p11 in depression-like states. Science. 2006 Jan 6;311(5757):77-80.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Rat, Cat, Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: C-SNEDFKQAFHK
NCBI Gene ID #:
3351
NCBI Official Name:
5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
NCBI Official Symbol:
HTR1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000854.1
Protein GI Number:
4504533
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
.
Swissprot #:
P28222