Further Information
SMARCB1, RDT, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1
SMARCB1 antibody can be used for detection of SMARCB1 by ELISA at 1:62500. SMARCB1 antibody can be used for detection of SMARCB1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors.The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.
- Kimura, K., et al., (2006) Genome Res. 16 (1), 55-65.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMARCB1.
6598
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCB1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
NP_001007469
55956801
Antibody is purified by peptide affinity chromatography method.
Transcription ,Cell Cycle ,Cancer ,Apoptosis
Q12824-2
Optimal dilutions for each application to be determined by the researcher.