Further Information
MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, GOUT1, CDw338, UAQTL1, EST157481, MRX
Western Blot: 1:500
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
- Henriksen U., Gether U., Litman T. J. Cell Sci. 118:1417-1426 (2005) Wakabayashi K., Nakagawa H., Tamura A., Koshiba S., Hoshijima K., Komada M., Ishikawa T. J. Biol. Chem. 282:27841-27846 (2007)
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
ABCG2 (CD338) antibody was raised against a peptide sequence around aa.160~164 ( R-I-N-R-V) derived from Human ABCG2 (CD338).
9429
ATP-binding cassette, sub-family G (WHITE), member 2
ABCG2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
65 - 80 kDa
NP_004818.2
62526033
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Stem Cell
This antibody detects endogenous level of total ABCG2(CD338) protein.
Q9UNQ0