Further Information
CDC2, CDC28A, P34CDC2, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A, CDC28, CDC2A, CDK1, Cyclin-dependent kinase 1
Western Blot: 1:500~1:1000
Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
- Y Gu, et al. (1992) EMBO J. 11 (11): 3995?4005. P Jin, et al. (1996) Cell Biology, Vol 134: 963-970, Tyagi, et al. (2005) Alpna1Carcinogenesis, Volume 26: 1978-1987 (10) Xiang S. et al. (1997) The EMBO Journal 16: 182?192
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
CDC2 (Phospho-Tyr15) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 15 (G-T-Y (p) -G-V) derived from Human CDC2.
Phospho-Specific
983
cyclin-dependent kinase 1
CDK1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
NP_001163877.1
281427278
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Phospho-Specific,Apoptosis,Cancer,Cell Cycle
This antibody detects endogenous level of CDC2 only when phosphorylated at tyrosine 15.
P06493