ProSci

FAK Antibody

Product Code:
 
PSI-79-584
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of extract from HepG2, 293, C6, HUVEC and HT29 cells using FAK (Ab-397).
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Western blot analysis of extract from HepG2, 293, C6, HUVEC and HT29 cells using FAK (Ab-397).

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PSI-79-584-0.1mg0.1mg£481.00
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This product comes from: United States.
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Further Information

Additional Names:
FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, PTK2
Application Note:
Western Blot: 1:500~1:1000
Background:
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.
Background References:
  • von Sengbusch A, et al. (2005) Am J Pathol ; 166 (2): 585-596Fornaro M, et al. (2000) Mol Biol Cell ; 11 (7): 2235-2249Zhang X, et al. (1999) Proc Natl Acad Sci U S A; 96 (16): 9021-9026.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
FAK (Ab-397) antibody was raised against a peptide sequence around aa. 395~399 (D-D-Y-A-E) derived from FAK.
NCBI Gene ID #:
5747
NCBI Official Name:
protein tyrosine kinase 2
NCBI Official Symbol:
PTK2
NCBI Organism:
This antibody was raised against a peptide sequence around aa. 395~399 (D-D-Y-A-E) derived from FAK
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
125 kDa
Protein Accession #:
NP_005598.3
Protein GI Number:
27886593
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous levels of total FAK protein.
Swissprot #:
Q05397