ProSci

KIF5A Antibody

Product Code:
 
PSI-45-799
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Aliquot and store at -20˚C. Minimize freezing and thawing.
 

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CodeSizePrice
PSI-45-799-0.1mg0.1mg£505.00
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Further Information

Additional Names:
KIF5A, kinesin family member 5A, NKHC, N-KHC, D12S1889, MY050, SPG10, KIF5A variant protein, kinesin, heavy chain, neuron-specific
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Preliminary experiments gave bands at approx 140, 50, 35 and 20kDa in Human Brain lysates at 1ug of primary. Please note that currently we cannot find an explanation in the literature for the multiple bands we observe given the predicted size of approx. 119Kda according to NP_004975. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any splice variants/modified forms been reported?
Background References:
  • Reid E, Kloos M, Ashley-Koch A, Hughes L, Bevan S, Svenson IK, Graham FL, Gaskell PC, Dearlove A, Pericak-Vance MA, Rubinsztein DC, Marchuk DA. A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10). Am J Hum Genet. 2002 Nov;71(5):1189-94.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse, Rat, Dog, Cow
Immunogen:
The immunogen for this antibody is: C-QAKLFPLHQETAAS
NCBI Gene ID #:
3798
NCBI Official Name:
kinesin family member 5A
NCBI Official Symbol:
KIF5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_004975.2
Protein GI Number:
45446749
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
Swissprot #:
Q12840