Further Information
FBXW11, BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, KIAA0696
FBXW11 antibody can be used for detection of FBXW11 by ELISA at 1:312500. FBXW11 antibody can be used for detection of FBXW11 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
- Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007).
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBXW11.
23291
F-box and WD repeat domain containing 11
FBXW11
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
NP_036432
48928050
Antibody is purified by peptide affinity chromatography method.
Signal Transduction
Q9UKB1
Optimal dilutions for each application to be determined by the researcher.