ProSci

NEURL2 Antibody

Product Code:
 
PSI-30-830
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NEURL2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 1
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.
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Antibody used in WB on Human Muscle at 0.2-1 ug/ml.

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PSI-30-830-100ul100ul£662.00
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This product comes from: United States.
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Further Information

Additional Names:
NEURL2, C20orf163, MGC125934, MGC125935, OZZ, Ozz-E3, OZZ-E3
Application Note:
NEURL2 antibody can be used for detection of NEURL2 by ELISA at 1:312500. NEURL2 antibody can be used for detection of NEURL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
NEURL2 contains 1 NHR (neuralized homology repeat) domain and 1 SOCS box domain. NEURL2 plays an important role in the process of myofiber differentiation and maturation. NEURL2 is the probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. NEURL2 probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, it controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.
Background References:
  • Song, R., (2006) J. Biol. Chem. 281 (47), 36391-36400.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NEURL2.
NCBI Gene ID #:
140825
NCBI Official Name:
neuralized E3 ubiquitin protein ligase 2
NCBI Official Symbol:
NEURL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
NP_542787
Protein GI Number:
18152787
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Signal Transduction ,Immunology
Swissprot #:
Q9BR09
User NOte:
Optimal dilutions for each application to be determined by the researcher.