ProSci

MLL4 Antibody

Product Code:
 
PSI-27-926
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MLL4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in WB on Human HepG2 cells at 5 ug/ml.
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Antibody used in WB on Human HepG2 cells at 5 ug/ml.

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PSI-27-926-100ul100ul£609.00
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Further Information

Additional Names:
MLL4, HRX2, MLL2, MLL4, TRX2, WBP7, MLL1B
Application Note:
MLL4 antibody can be used for detection of MLL4 by ELISA at 1:12500. MLL4 antibody can be used for detection of MLL4 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
MLL4 a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. MLL4 is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer
Background References:
  • FitzGerald, K.T., et al., (1999) Genomics 59 (2), 187-192.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MLL4.
NCBI Gene ID #:
9757
NCBI Official Name:
lysine (K)-specific methyltransferase 2B
NCBI Official Symbol:
KMT2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
64 kDa, 294 kDa
Protein Accession #:
Q9UMN6-2
Protein GI Number:
12643900
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
Q9UMN6-2
User NOte:
Optimal dilutions for each application to be determined by the researcher.