ProSci

SUV39H1 Antibody

Product Code:
 
PSI-27-610
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SUV39H1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in IHC on Human Intestine.
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Antibody used in IHC on Human Intestine.

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PSI-27-610-100ul100ul£609.00
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Further Information

Additional Names:
SUV39H1, KMT1A, MG44, SUV39H, H3-K9-HMTase 1
Application Note:
SUV39H1 antibody can be used for detection of SUV39H1 by ELISA at 1:312500. SUV39H1 antibody can be used for detection of SUV39H1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SUV39H1, a human homolog of the Drosophila position effect variegation modifier Su (var)3-9 and of the S. pombe silencing factor clr4, encodes a heterochromatic protein that transiently accumulates at centromeric positions during mitosis.This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Kang, M.Y., (2007) Int. J. Cancer 121 (10), 2192-2197.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SUV39H1.
NCBI Gene ID #:
6839
NCBI Official Name:
suppressor of variegation 3-9 homolog 1 (Drosophila)
NCBI Official Symbol:
SUV39H1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
NP_003164
Protein GI Number:
4507321
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Cell Cycle ,Cancer
Swissprot #:
O43463
User NOte:
Optimal dilutions for each application to be determined by the researcher.