Further Information
Alternate Names/Synonyms:
Z-LLE-AMC; Proteasome Substrate II
Solid lyophilized powder.
348086-66-8
32160000
liquid
Avoid freeze/thaw cycles.Protect from light.
InChI=1S/C35H44N4O9/c1-20(2)15-27(38-34(45)28(16-21(3)4)39-35(46)47-19-23-9-7-6-8-10-23)33(44)37-26(13-14-30(40)41)32(43)36-24-11-12-25-22(5)17-31(42)48-29(25)18-24/h6-12,17-18,20-21,26-28H,13-16,19H2,1-5H3,(H,36,43)(H,37,44)(H,38,45)(H,39,46)(H,40,41)/t26-,27-,28-/m0/s1
FOYHOBVZPWIGJM-KCHLEUMXSA-N
Chemical. CAS: 348086-66-8. Formula: C35H44N4O9. MW: 664.8. Fluorogenic substrate for the peptidylglutamyl-peptide hydrolysing (PGPH) (caspase-like) activity of the 20S proteasome. Excitation: 380nm. Emission: 460nm.
MFCD01074989
C35H44N4O9
664.8
Use: Add from DMSO stock directly to in vitro or in vivo assays at desired concentration. Typical concentrations range from 10-100µM.
Vial
Fluorogenic substrate for the peptidylglutamyl-peptide hydrolysing (PGPH) (caspase-like) activity of the 20S proteasome. Excitation: 380nm. Emission: 460nm.
>95% (HPLC)
Z-Leu-Leu-Glu-7-amido-4-methylcoumarin
CC(C)C[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NC1=CC=C2C(C)=CC(=O)OC2=C1
Soluble in DMSO.
Non-hazardous
Biochemical Reagents
12352200
Stable for at least 1 year after receipt when stored at -20°C.