ProSci

CD29 Antibody [TS2/16] (PE)

Product Code:
 
PSI-76-792
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
TS2/16
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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PSI-76-792-100tests100tests£560.00
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Further Information

Additional Names:
CD29, FNRB, MDF2, VLAB, GPIIA, MSK12, VLA-BETA, ITGB1
Background:
The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells. It forms the VLA-(1-6) molecules with integrin alpha-(1-6) and is involved in the adhesion between cell-cell and cell-matrix. The TS2/16 antibody has been found to activate beta 1 integrins.
Background References:
  • Ridger, V. C., Wagner, B. E., Wallace, W. A., Hellewell, P. G. (2001). Differential effects of CD18, CD29, and CD49 integrin subunit inhibition on neutrophil migration in pulmonary inflammation.The Journal of Immunology,166(5), 3484-3490.
  • Noto, K., Kato, K., Okumura, K., Yagita, H. (1995). Identification and functional characterization of mouse CD29 with a mAb.International immunology,7(5), 835-842.
  • Sangaletti, S., Di Carlo, E., Gariboldi, S., Miotti, S., Cappetti, B., Parenza, M., ... Colombo, M. P. (2008). Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis.Cancer research,68(21), 9050-9059.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
3688
NCBI Official Name:
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
NCBI Official Symbol:
ITGB1
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Cancer
SPECIFICITY:
The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells.
Swissprot #:
P05556
User NOte:
Optimal dilutions for each application to be determined by the researcher.