ProSci

IRAK1 (phospho Ser376) Antibody

Product Code:
 
PSI-79-849
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry (IHC)
Storage:
 
Store antibody at -20°C for up to one year.
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Immunohistochemical analysis of paraffin-embedded human brain tissue using IRAK1 (Phospho-Ser376) antibody (left) or the same antibody preincubated with blocking peptide (right).
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Immunohistochemical analysis of paraffin-embedded human brain tissue using IRAK1 (Phospho-Ser376) antibody (left) or the same antibody preincubated with blocking peptide (right).

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PSI-79-849-0.1mg0.1mg£488.00
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Further Information

Additional Names:
IL1RAK, IRAK, mPLK
Background:
IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.
Background References:
  • Cao Z., Science 271:1128-1131(1996).
  • Reichwald K., Mamm. Genome 11:182-190(2000).
  • Jensen L.E., J. Biol. Chem. 276:29037-29044(2001).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IRAK1 (phospho Ser376) antibody was raised against a peptide sequence around phosphorylation site of Serine 376 (Q-S-S (p)-M-V) derived from Human IRAK1.
Modifications:
Phospho-Specific
NCBI Gene ID #:
3654
NCBI Official Name:
interleukin-1 receptor-associated kinase 1
NCBI Official Symbol:
IRAK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
76 kDa
Protein Accession #:
NP_001560.2
Protein GI Number:
8928535
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of IRAK1 only when phosphorylated at serine 376.
Swissprot #:
P51617