ProSci

HP1alpha (phospho Ser92) Antibody

Product Code:
 
PSI-79-887
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry (IHC)
Storage:
 
Store antibody at -20°C for up to one year.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HP1alpha (Phospho-Ser92) antibody (left) or the same antibody preincubated with blocking peptide (right).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HP1alpha (Phospho-Ser92) antibody (left) or the same antibody preincubated with blocking peptide (right).

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CodeSizePrice
PSI-79-887-0.1mg0.1mg£488.00
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Further Information

Additional Names:
HP1A, HP1 alpha, antigen p25
Background:
Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing.
Background References:
  • Saunders W.S., J. Cell Sci. 104:573-582(1993).
  • Ye Q., J. Biol. Chem. 271:14653-14656(1996).
  • Ye Q., J. Biol. Chem. 272:14983-14989(1997).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
HP1alpha (phospho Ser92) antibody was raised against a peptide sequence around phosphorylation site of Serine 92 (R-S-S (p)-N-F) derived from Human HP1alpha .
Modifications:
Phospho-Specific
NCBI Gene ID #:
23468
NCBI Official Name:
chromobox homolog 5
NCBI Official Symbol:
CBX5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
NP_001120793.1
Protein GI Number:
6912292
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of HP1alpha only when phosphorylated at serine 92.
Swissprot #:
P45973